A step-by-step guide to building a full-stack SPA with Flask and Vue.js: set up Flask with SQLAlchemy and Flask-WTF (CSRF), define models (e.g., a User on SQLite), configure app.py and templates, scaffold a Vue app that mounts to #app, serve the compiled bundle as static assets via index.html, and connect frontend and backend through API calls—establishing a flexible, scalable base for CRUD-driven features.